CD57 antibody (N-Term)

Catalog No. ABIN2790517

This Rabbit Polyclonal antibody specifically detects CD57 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for CD57 antibody (N-Term) (ABIN2790517)

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD57 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD57 Antibody

Binding Specificity: N-Term

Sequence: LAPLLAVHKD EGSDPRRETP PGADPREYCT SDRDIVEVVR TEYVYTRPPP

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against B3GAT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human B3GAT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 334 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD57

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Alternative Name: B3GAT1

Background: The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized.
Alias Symbols: CD57, GLCATP, GLCUATP, HNK1, LEU7, NK-1, NK1
Protein Interaction Partner: SH3GL1, HLA-DMA, B3GAT1,
Protein Size: 334

Molecular Weight: 37 kDa

Gene ID: 27087

NCBI Accession: NM_054025, NP_473366

UniProt: Q9P2W7

Pathways: Glycosaminoglycan Metabolic Process