MCCC1 antibody (N-Term)

Catalog No. ABIN2790562

This Rabbit Polyclonal antibody specifically detects MCCC1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse and Saccharomyces cerevisiae.

Quick Overview for MCCC1 antibody (N-Term) (ABIN2790562)

Target: MCCC1 (Methylcrotonoyl-CoA Carboxylase 1 (Alpha) (MCCC1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MCCC1 Antibody

Binding Specificity: N-Term

Purpose: MCCC1 Antibody - N-terminal region

Sequence: IKAVRGGGGK GMRIVRSEQE FQEQLESARR EAKKSFNDDA MLIEKFVDTP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against DKFZp686B20267. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human MCCC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66863-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MCCC1

Target: MCCC1 (Methylcrotonoyl-CoA Carboxylase 1 (Alpha) (MCCC1))

Alternative Name: MCCC1

Background:

Background Information: This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Gene Name: methylcrotonoyl-CoA carboxylase 1

Alternative Symbols: MCCA, MCC-B, MCCCalpha

Protein Name: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

Molecular Weight: 63kDa

Gene ID: 56922

NCBI Accession: NP_001280202

UniProt: Q68D27