Nogo B Receptor antibody (Middle Region)

Catalog No. ABIN2790565

The Rabbit Polyclonal anti-Nogo B Receptor antibody is suitable to detect Nogo B Receptor in samples from Human, Mouse, Rat, Horse, Pig, Cow, Dog, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for Nogo B Receptor antibody (Middle Region) (ABIN2790565)

Target: Nogo B Receptor (NUS1)

Reactivity: Human, Mouse, Rat, Horse, Pig, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nogo B Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nogo B Receptor Antibody

Binding Specificity: Middle Region

Purpose: Nus1 Antibody - middle region

Sequence: RLMDEILKQQ QELLGQDCSK YSAEFANSND KDDQDLNCPS AVKVLSPEDG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Nus1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Nus1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66889-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Nogo B Receptor

Target: Nogo B Receptor (NUS1)

Alternative Name: Nus1

Background:

Background Information: Nus1 acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. It regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.

Gene Name: nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)

Alternative Symbols: Ng, AU019165, AW538011, BC003223, D10Ertd438, D10Ertd438e, 1600027K07Rik

Protein Name: Nogo-B receptor

Molecular Weight: 33kDa

Gene ID: 52014

NCBI Accession: NP_084526

UniProt: Q99LJ8