INTU antibody (C-Term)

Catalog No. ABIN2790639

The Rabbit Polyclonal anti-INTU antibody is suitable to detect INTU in samples from Human and Dog. It has been validated for WB.

Quick Overview for INTU antibody (C-Term) (ABIN2790639)

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-INTU Antibody

Binding Specificity: C-Term

Purpose: INTU Antibody - C-terminal region

Sequence: TLEEVAQLSG SIHPQLIKNF HQCCLSIRAV FQQTLVEEKK KGLNSGDHSD

Predicted Reactivity: Dog: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against INTU. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human INTU

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67141-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTU

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Alternative Name: INTU

Background:

Background Information: INTU plays a key role in ciliogenesis and embryonic development. INTU is a regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. It plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension and has an indirect effect on hedgehog signaling.

Alternative Symbols: INT, OFD17, PDZD6, PDZK6, SRTD20, CPLANE4

Protein Name: Protein inturned

Molecular Weight: 104kDa

Gene ID: 27152

NCBI Accession: NP_056508

UniProt: Q9ULD6