MRPL36 antibody (C-Term)

Catalog No. ABIN2790654

This Rabbit Polyclonal antibody specifically detects MRPL36 in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Rat, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for MRPL36 antibody (C-Term) (ABIN2790654)

Target: MRPL36 (Mitochondrial Ribosomal Protein L36 (MRPL36))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Rat, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL36 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL36 Antibody

Binding Specificity: C-Term

Purpose: MRPL36 Antibody - C-terminal region

Sequence: PGLLPHLLPA LGFKNKTVLK KRCKDCYLVK RRGRWYVYCK THPRHKQRQM

Predicted Reactivity: Cow: 79%, Dog: 82%, Guinea Pig: 75%, Horse: 86%, Human: 100%, Mouse: 83%, Pig: 79%, Rabbit: 79%, Rat: 83%, Yeast: 77%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against MRPL36. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPL36

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67178-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL36

Target: MRPL36 (Mitochondrial Ribosomal Protein L36 (MRPL36))

Alternative Name: MRPL36

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p.

Alternative Symbols: RPMJ, BRIP1, L36mt, PRPL36, MRP-L36

Protein Name: 39S ribosomal protein L36, mitochondrial

Molecular Weight: 11kDa

Gene ID: 64979

NCBI Accession: NP_115868

UniProt: Q9P0J6