P4HA3 antibody (N-Term)

Catalog No. ABIN2790667

The Rabbit Polyclonal anti-P4HA3 antibody is suitable to detect P4HA3 in samples from Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for P4HA3 antibody (N-Term) (ABIN2790667)

Target: P4HA3 (Prolyl 4-Hydroxylase, alpha Polypeptide III (P4HA3))

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HA3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-P4HA3 Antibody

Binding Specificity: N-Term

Purpose: P4HA3 Antibody - N-terminal region

Sequence: EDSTTPVANP LLAFTLIKRL QSDWRNVVHS LEASENIRAL KDGYEKVEQD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against P4HA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human P4HA3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67221-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for P4HA3

Target: P4HA3 (Prolyl 4-Hydroxylase, alpha Polypeptide III (P4HA3))

Alternative Name: P4HA3

Background:

Targeted Subunit: alpha-3

Background Information: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Alternative Symbols: -

Protein Name: Prolyl 4-hydroxylase subunit alpha-3

Molecular Weight: 60kDa

Gene ID: 283208

NCBI Accession: NP_878907

UniProt: Q7Z4N8