POLA2 antibody (N-Term)

Catalog No. ABIN2790673

The Rabbit Polyclonal anti-POLA2 antibody has been validated for WB. It is suitable to detect POLA2 in samples from Human, Mouse, Horse and Pig.

Quick Overview for POLA2 antibody (N-Term) (ABIN2790673)

Target: POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit) (POLA2))

Reactivity: Human, Mouse, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLA2 Antibody

Binding Specificity: N-Term

Sequence: VGLTSEILNS FEHEFLSKRL SKARHSTCKD SGHAGARDIV SIQELIEVEE

Predicted Reactivity: Horse: 86%, Human: 100%, Mouse: 79%, Pig: 79%

Characteristics: This is a rabbit polyclonal antibody against POLA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human POLA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 598 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POLA2

Target: POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit) (POLA2))

Alternative Name: POLA2

Background: POLA2 may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.
Alias Symbols: FLJ21662, FLJ37250
Protein Interaction Partner: CIAO1, UBC, REPIN1, HEXIM1, POP7, PRIM2, POLA1, EPB41L1, UBE2O, DCP2, MMS19, PRIM1, APP, NR4A1, FRZB, HDAC6, KCNE3, RAE1, HGH1, ASCC2, RBM23, DHX34, FAM219A, STK40, PRPF38A, ULK2, HELB, AKTIP, SETDB1, CRELD1, DDX24, EIF6, XPNPEP1, KLF6, EZH2, NHP2L1, IGFB
Protein Size: 598

Molecular Weight: 66 kDa

Gene ID: 23649

NCBI Accession: NM_002689, NP_002680

UniProt: Q14181

Pathways: Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Protein targeting to Nucleus, Synthesis of DNA, SARS-CoV-2 Protein Interactome