SH3D19 antibody (C-Term)

Catalog No. ABIN2790698

The Rabbit Polyclonal anti-SH3D19 antibody (ABIN2790698) specifically detects SH3D19 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse and Pig samples.

Quick Overview for SH3D19 antibody (C-Term) (ABIN2790698)

Target: SH3D19 (SH3 Domain Containing 19 (SH3D19))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3D19 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SH3D19 Antibody

Binding Specificity: C-Term

Purpose: SH3D19 Antibody - C-terminal region

Sequence: RGEVRGRTGI FPLNFVEPVE DYPTSGANVL STKVPLKTKK EDSGSNSQVN

Predicted Reactivity: Cow: 86%, Guinea Pig: 83%, Horse: 83%, Human: 100%, Mouse: 83%, Pig: 86%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against SH3D19. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SH3D19

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67290-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SH3D19

Target: SH3D19 (SH3 Domain Containing 19 (SH3D19))

Alternative Name: SH3D19

Background:

Background Information: This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: EBP, EVE1, Kryn, Eve-1, SH3P19

Molecular Weight: 87kDa

Gene ID: 152503

NCBI Accession: NP_001009555

UniProt: C9JDW6