This Rabbit Polyclonal antibody specifically detects SH3D19 in WB. It exhibits reactivity toward Human, Rat, Cow, Guinea Pig, Rabbit, Horse, Pig and Dog.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
SH3D19
(SH3 Domain Containing 19 (SH3D19))
Alternative Name
SH3D19
Background
This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Protein Interaction Partner: SH3YL1, SH3KBP1, ELAVL1, Cd2ap, GRB2, CDC42, ADAM15, ADAM17, SH3GL3, ADAM12, ADAM9, ADAM10, SH3GL1, SOS2, Protein Size: 420