CCT6A antibody (Middle Region)

Catalog No. ABIN2790742

The Rabbit Polyclonal anti-CCT6A antibody has been validated for WB. It is suitable to detect CCT6A in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for CCT6A antibody (Middle Region) (ABIN2790742)

Target: CCT6A (Chaperonin Containing TCP1, Subunit 6A (Zeta 1) (CCT6A))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT6A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCT6A Antibody

Binding Specificity: Middle Region

Sequence: YILTCNVSLE YEKTEVNSGF FYKSAEEREK LVKAERKFIE DRVKKIIELK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CCT6A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CCT6A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 531 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCT6A

Target: CCT6A (Chaperonin Containing TCP1, Subunit 6A (Zeta 1) (CCT6A))

Alternative Name: CCT6A

Background: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located.
Alias Symbols: CCT-zeta, CCT-zeta-1, CCT6, Cctz, HTR3, MoDP-2, TCP-1-zeta, TCP20, TCPZ, TTCP20
Protein Interaction Partner: HUWE1, UBC, TP53, FUS, SUMO2, SUMO3, LGALS3BP, CDC20, NEDD1, TUBG1, MDM2, WWOX, CCT8, CCT2, CCT4, CCT7, CCT3, EEF1D, FBXO6, UBD, HDAC3, ILK, CDK5, CDK2, PAN2, METTL20, METTL18, CAMKMT, METTL21B, PEX14, NOS2, ITGA4, FN1, US3, FAM86B2, VCAM1, VCP, SMURF1, N
Protein Size: 531

Molecular Weight: 58 kDa

Gene ID: 908

NCBI Accession: NM_001762, NP_001753

UniProt: P40227