CCT6A antibody (AA 140-220)

Catalog No. ABIN7217262

The Rabbit Polyclonal anti-CCT6A antibody is suitable to detect CCT6A in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for CCT6A antibody (AA 140-220) (ABIN7217262)

Target: CCT6A (Chaperonin Containing TCP1, Subunit 6A (Zeta 1) (CCT6A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT6A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CCT6A Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-TCP-1 ζ Polyclonal Antibody

Specificity: TCP-1 ζ Polyclonal Antibody detects endogenous levels of TCP-1 ζ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TCP-1 zeta at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCT6A

Target: CCT6A (Chaperonin Containing TCP1, Subunit 6A (Zeta 1) (CCT6A))

Alternative Name: TCP-1 zeta

Background: CCT6A, CCT6, CCTZ, T-complex protein 1 subunit zeta, TCP-1-zeta, Acute morphine dependence-related protein 2, CCT-zeta-1, HTR3, Tcp20T-complex protein 1 subunit zeta encoded by CCT6A is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located.

Molecular Weight: 60kD

Gene ID: 908

UniProt: P40227