IQSEC2 antibody (Middle Region)

Catalog No. ABIN2790791

This Rabbit Polyclonal antibody specifically detects IQSEC2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio).

Quick Overview for IQSEC2 antibody (Middle Region) (ABIN2790791)

Target: IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQSEC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IQSEC2 Antibody

Binding Specificity: Middle Region

Purpose: IQSEC2 Antibody - middle region

Sequence: ARTIQTAFRQ YRMNKNFERL RSSASESRMS RRIILSNMRM QFSFEEYEKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against IQSEC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human IQSEC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67590-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IQSEC2

Target: IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))

Alternative Name: IQSEC2

Background:

Background Information: This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation.

Alternative Symbols: MRX1, BRAG1, MRX18, MRX78, IQ-ArfGEF

Protein Name: IQ motif and SEC7 domain-containing protein 2

Molecular Weight: 163kDa

Gene ID: 23096

NCBI Accession: NP_001104595

UniProt: Q5JU85