RAB3GAP2 antibody (Middle Region)

Catalog No. ABIN2790855

The Rabbit Polyclonal anti-RAB3GAP2 antibody (ABIN2790855) specifically detects RAB3GAP2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow and Guinea Pig samples.

Quick Overview for RAB3GAP2 antibody (Middle Region) (ABIN2790855)

Target: RAB3GAP2 (RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB3GAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAB3GAP2 Antibody

Binding Specificity: Middle Region

Purpose: RAB3GAP2 Antibody - middle region

Sequence: SWLQDCVLSL SPTNDLMVIA REQKAVFLVP KWKYSDKGKE EMQFAVGWSG

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against RAB3GAP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human RAB3GAP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67770-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAB3GAP2

Target: RAB3GAP2 (RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2))

Alternative Name: RAB3GAP2

Background:

Background Information: The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.

Gene Name: RAB3 GTPase activating protein subunit 2 (non-catalytic)

Alternative Symbols: p150, SPG69, WARBM2, RAB3GAP150, RAB3-GAP150

Protein Name: Rab3 GTPase-activating protein non-catalytic subunit

Molecular Weight: 22kDa

Gene ID: 25782

UniProt: Q9H2M9