SYT14 antibody (Middle Region)

Catalog No. ABIN2790867

Product Details anti-SYT14 Antibody

Target: SYT14 (Synaptotagmin XIV (SYT14))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT14 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HCSNSPRCSY NKCPSEGSTG HEIESFHNKG YEEDVPSDST AVLSPEDMSA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SYT14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SYT14

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 555 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYT14

Target: SYT14 (Synaptotagmin XIV (SYT14))

Alternative Name: SYT14 (SYT14 Products)

Background: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1,3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4.
Alias Symbols: SCAR11, sytXIV
Protein Interaction Partner: SYT16, SYT14,
Protein Size: 555

Molecular Weight: 62 kDa

Gene ID: 255928

NCBI Accession: NM_153262, NP_694994

UniProt: Q8NB59