WIPI2 antibody (C-Term)

Catalog No. ABIN2790887

This Rabbit Polyclonal antibody specifically detects WIPI2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for WIPI2 antibody (C-Term) (ABIN2790887)

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPI2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WIPI2 Antibody

Binding Specificity: C-Term

Sequence: AFSMDGMFLS ASSNTETVHI FKLETVKEKP PEEPTTWTGY FGKVLMASTS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against WIPI2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human WIPI2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 384 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WIPI2

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Alternative Name: WIPI2

Background: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids.
Alias Symbols: ATG18B, Atg21, WIPI-2
Protein Interaction Partner: ATG16L1, ARL6IP1, RABAC1, HUWE1, ATG5, ATG12, UBC, TXLNA, ZFAND6, TIMM13, COPS5, TERF2IP, POT1, BTBD8, GCN1L1, NUDC, PFKP, DNAJB1, FLNC, DNM2, STRN4, COPS6,
Protein Size: 384

Molecular Weight: 42 kDa

Gene ID: 26100

NCBI Accession: NM_001033520, NP_001028692