YARS2 antibody (C-Term)

Catalog No. ABIN2790888

The Rabbit Polyclonal anti-YARS2 antibody has been validated for WB. It is suitable to detect YARS2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Pig.

Quick Overview for YARS2 antibody (C-Term) (ABIN2790888)

Target: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-YARS2 Antibody

Binding Specificity: C-Term

Sequence: QPDDSVERYL KLFTFLPLPE IDHIMQLHVK EPERRGPQKR LAAEVTKLVH

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against YARS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human YARS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 477 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YARS2

Target: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Alternative Name: YARS2

Background: This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2).
Alias Symbols: MLASA2, MT-TYRRS, TYRRS
Protein Interaction Partner: FAM9B, UBC, BMI1, DDRGK1, CAND1, CUL3, Ybx1, ICT1, USP49, CDC20,
Protein Size: 477

Molecular Weight: 52 kDa

Gene ID: 51067

NCBI Accession: NM_001040436, NP_001035526

UniProt: Q9Y2Z4