YOD1 antibody (C-Term)

Catalog No. ABIN2790890

Product Details anti-YOD1 Antibody

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YOD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELADEARRRR QFTDVNRFTL RCMVCQKGLT GQAEAREHAK ETGHTNFGEV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against YOD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human YOD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 348 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YOD1

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Alternative Name: YOD1 (YOD1 Products)

Background: Deubiquitinating enzymes are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.
Alias Symbols: DUBA8, OTUD2, PRO0907
Protein Interaction Partner: NPLOC4, VCP, UFD1L, RIPK1, UBE3A, UBC, NEDD4, SYVN1, TRA, AMFR, TRIM63, TRIM54, USP21, USP15, TRIM55, UBE2J1, ELAVL1, DERL1, FAF2, THOC3, BLOC1S5, YOD1,
Protein Size: 348

Molecular Weight: 38 kDa

Gene ID: 55432

NCBI Accession: NM_018566, NP_061036

UniProt: Q5VVQ6

Pathways: ER-Nucleus Signaling