PARPBP antibody (C-Term)

Catalog No. ABIN2790948

The Rabbit Polyclonal anti-PARPBP antibody is suitable to detect PARPBP in samples from Human, Horse, Rabbit, Pig and Rat. It has been validated for WB.

Quick Overview for PARPBP antibody (C-Term) (ABIN2790948)

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Reactivity: Human, Horse, Rabbit, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARPBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PARPBP Antibody

Binding Specificity: C-Term

Purpose: PARPBP Antibody - C-terminal region

Sequence: YMENDLSEGV NPSVGRSTIG TSFGNVHLDR SKNEKVSRKS TSQTGNKSSK

Predicted Reactivity: Horse: 85%, Human: 100%, Pig: 92%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PARPBP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68105-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PARPBP

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Alternative Name: PARPBP

Background:

Background Information: PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly(A) homopolymers and positively regulate the poly(ADP-ribosyl)ation activity of PARP1, however such function may be indirect.

Gene Name: PARP1 binding protein

Alternative Symbols: AROM, PARI, C12orf48

Protein Name: PCNA-interacting partner

Molecular Weight: 32kDa

Gene ID: 55010

UniProt: Q9NWS1