CNIH2 antibody (C-Term)

Catalog No. ABIN2790981

This Rabbit Polyclonal antibody specifically detects CNIH2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Dog, Zebrafish (Danio rerio), Cow, Horse and Rabbit.

Quick Overview for CNIH2 antibody (C-Term) (ABIN2790981)

Target: CNIH2 (Cornichon Homolog 2 (CNIH2))

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Zebrafish (Danio rerio), Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNIH2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNIH2 Antibody

Binding Specificity: C-Term

Purpose: CNIH2 Antibody - C-terminal region

Sequence: LWRYFHRPAD GSEVMYDAVS IMNADILNYC QKESWCKLAF YLLSFFYYLY

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CNIH2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CNIH2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68225-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNIH2

Target: CNIH2 (Cornichon Homolog 2 (CNIH2))

Alternative Name: CNIH2

Background:

Background Information: The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants.

Alternative Symbols: Cnil, CNIH-2

Protein Name: Protein cornichon homolog 2

Molecular Weight: 19kDa

Gene ID: 254263

NCBI Accession: NP_872359

UniProt: Q6PI25