H2AFB1 antibody (N-Term)

Catalog No. ABIN2791037

The Rabbit Polyclonal anti-H2AFB1 antibody (ABIN2791037) specifically detects H2AFB1 in WB. The antibody is reactive with Human samples.

Quick Overview for H2AFB1 antibody (N-Term) (ABIN2791037)

Target: H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-H2AFB1 Antibody

Binding Specificity: N-Term

Purpose: H2AFB1 Antibody - N-terminal region

Sequence: SSGAGGRGRT CSRTVRAELS FSVSQVERSL REGHYAQRLS RTAPVYLAAV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against H2AFB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human H2AFB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68411-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for H2AFB1

Target: H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))

Alternative Name: H2AFB1

Background:

Background Information: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most centromeric copy which is in intron 22 of the F8 gene.

Alternative Symbols: H2A.B, H2AFB1, H2A.Bbd

Protein Name: Histone H2A-Bbd type 1

Molecular Weight: 13kDa

Gene ID: 474382

NCBI Accession: NP_001017990

UniProt: P0C5Y9

Pathways: Telomere Maintenance