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H2AFB1 antibody (H2A Histone Family, Member B1) (N-Term) Primary Antibody

H2AFB1 Reactivity: Human WB Host: Rabbit Polyclonal
Catalog No. ABIN2791037
$229.00
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100 μL
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  • Target
    Binding Specificity
    N-Term
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This H2AFB1 antibody is un-conjugated
    Application
    Western Blotting (WB)
    Blocking Peptide
    Blocking peptide for this product available: ABIN1542032
    Sequence
    SSGAGGRGRT CSRTVRAELS FSVSQVERSL REGHYAQRLS RTAPVYLAAV
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against H2AFB1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human H2AFB1
  • Target
    Alternative Name
    H2AFB1 (H2AFB1 Antibody Abstract)
    Background
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most centromeric copy which is in intron 22 of the F8 gene.
    Alias Symbols: H2A.Bbd
    Protein Interaction Partner: CBX3, CBX1,
    Protein Size: 115
    Molecular Weight
    13 kDa
    Gene ID
    474382
    NCBI Accession
    NM_001017990, NP_001017990
    UniProt
    P0C5Y9
    Pathways
    Telomere Maintenance
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 115 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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