INTS1 antibody (N-Term)

Catalog No. ABIN2791043

This Rabbit Polyclonal antibody specifically detects INTS1 in WB. It exhibits reactivity toward Human, Mouse, Guinea Pig, Rat, Cow, Dog and Horse.

Quick Overview for INTS1 antibody (N-Term) (ABIN2791043)

Target: INTS1 (Integrator Complex Subunit 1 (INTS1))

Reactivity: Human, Mouse, Guinea Pig, Rat, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-INTS1 Antibody

Binding Specificity: N-Term

Sequence: TVRRPSAAAK PSGHPPPGDF IALGSKGQAN ESKTASTLLK PAPSGLPSER

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against INTS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human INTS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 2190 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTS1

Target: INTS1 (Integrator Complex Subunit 1 (INTS1))

Alternative Name: INTS1

Background: INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1 and U2 .
Alias Symbols: INT1, NET28
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, EED, SOX2, SIRT7, SUMO2, INTS10, CTDP1, NABP2, C7orf26, INTS3, ZNF687, INTS2, INTS12, INTS9, ASUN, INTS8, CPSF3L, INTS6, INTS1, INTS7, ZMYND8, PPP2R1B, PPP2R1A, PPP2CB, PPP2CA, PPP1CB, POLR2H, POLR2B, POLR2A, DDX26B, INTS4, VWA9, IN
Protein Size: 2190

Molecular Weight: 240 kDa

Gene ID: 26173

NCBI Accession: NM_001080453, NP_001073922

UniProt: Q8N201