KRT80 antibody (N-Term)

Catalog No. ABIN2791054

This Rabbit Polyclonal antibody specifically detects KRT80 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for KRT80 antibody (N-Term) (ABIN2791054)

Target: KRT80 (Keratin 80 (KRT80))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT80 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KRT80 Antibody

Binding Specificity: N-Term

Purpose: KRT80 Antibody - N-terminal region

Sequence: KVTVNPGLLV PLDVKLDPAV QQLKNQEKEE MKALNDKFAS LIGKVQALEQ

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against KRT80. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human KRT80

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68489-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRT80

Target: KRT80 (Keratin 80 (KRT80))

Alternative Name: KRT80

Background:

Background Information: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.

Alternative Symbols: KB20

Protein Name: Keratin, type II cytoskeletal 80

Molecular Weight: 46kDa

Gene ID: 144501

NCBI Accession: NP_001074961

UniProt: Q6KB66