KRT80 antibody (N-Term)

Catalog No. ABIN2791054

Product Details anti-KRT80 Antibody

Target: KRT80 (Keratin 80 (KRT80))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT80 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KVTVNPGLLV PLDVKLDPAV QQLKNQEKEE MKALNDKFAS LIGKVQALEQ

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against KRT80. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human KRT80

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 422 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRT80

Target: KRT80 (Keratin 80 (KRT80))

Alternative Name: KRT80 (KRT80 Products)

Synonyms: KB20 antibody, 1200016G03Rik antibody, 2310041I20Rik antibody, Kb20 antibody, Kb2 antibody, keratin 80 antibody, KRT80 antibody, Krt80 antibody

Background: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.
Alias Symbols: KB20
Protein Interaction Partner: KRT20, MEOX2, KRT15, COPS5, UBC, UCHL5,
Protein Size: 422

Molecular Weight: 46 kDa

Gene ID: 144501

NCBI Accession: NM_001081492, NP_001074961