NDUFA12 antibody (N-Term)

Catalog No. ABIN2791134

Product Details anti-NDUFA12 Antibody

Target: NDUFA12 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 12 (NDUFA12))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLKRGLQQIT GHGGLRGYLR VFFRTNDAKV GTLVGEDKYG NKYYEDNKQF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 100%, Yeast: 91%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NDUFA12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NDUFA12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 145 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDUFA12

Target: NDUFA12 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 12 (NDUFA12))

Alternative Name: NDUFA12 (NDUFA12 Products)

Synonyms: RGD1311462 antibody, si:dkey-183c16.3 antibody, zgc:112053 antibody, B17.2 antibody, DAP13 antibody, 2410011G03Rik antibody, AW112974 antibody, NADH:ubiquinone oxidoreductase subunit A12 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 antibody, Ndufa12 antibody, NDUFA12 antibody, ndufa12 antibody

Background: This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.
Alias Symbols: B17.2, DAP13
Protein Interaction Partner: UBC, MMGT1, TOMM22, MRPL15, ERLIN1, ATP5H, SURF1, NDUFS4, NDUFS1, NDUFB9, NDUFA9, NDUFA2, MPV17, CYC1, COX15, ATP5C1, ATP5B, ABCD1, ZNF768,
Protein Size: 145

Molecular Weight: 15 kDa

Gene ID: 55967

NCBI Accession: NM_018838, NP_061326

UniProt: Q9UI09