XRCC6BP1 antibody (C-Term)

Catalog No. ABIN2791261

The Rabbit Polyclonal anti-XRCC6BP1 antibody is suitable to detect XRCC6BP1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for XRCC6BP1 antibody (C-Term) (ABIN2791261)

Target: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC6BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-XRCC6BP1 Antibody

Binding Specificity: C-Term

Purpose: ATP23 Antibody - C-terminal region

Sequence: NISKEVAKKA VDEVFESCFN DHEPFGRIPH NKTYARYAHR DFENRDRYYS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against XRCC6BP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human XRCC6BP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP69117-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for XRCC6BP1

Target: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Alternative Name: ATP23

Background:

Background Information: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Gene Name: ATP23 metallopeptidase and ATP synthase assembly factor homolog

Alternative Symbols: KUB3, XRCC6BP1

Protein Name: mitochondrial inner membrane protease ATP23 homolog

Molecular Weight: 27kDa

Gene ID: 91419

NCBI Accession: NP_150592

UniProt: Q9Y6H3