BEAN1 antibody (C-Term)

Catalog No. ABIN2791320

This Rabbit Polyclonal antibody specifically detects BEAN1 in WB. It exhibits reactivity toward Human.

Quick Overview for BEAN1 antibody (C-Term) (ABIN2791320)

Target: BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BEAN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BEAN1 Antibody

Binding Specificity: C-Term

Purpose: BEAN1 Antibody - C-terminal region

Sequence: TDAPPPYSLT DSCPTLDGTS DSGSGHSPGR HQQEQRTPAQ GGLHTVSMDT

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against BEAN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human BEAN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP69338-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BEAN1

Target: BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))

Alternative Name: BEAN1

Background:

Background Information: The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: BEAN, SCA31

Protein Name: Protein BEAN1

Molecular Weight: 28kDa

Gene ID: 146227

NCBI Accession: NP_001171491

UniProt: Q3B7T3