FGD5 antibody (FYVE, RhoGEF and PH Domain Containing 5) (C-Term)

Catalog No. ABIN2791545

Product Details anti-FGD5 Antibody

Target:

FGD5

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FVIKGKVLYT YMASEDKVAL ESMPLLGFTI APEKEEGSSE VGPIFHLYHK

Predicted Reactivity: Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FGD5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FGD5

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FGD5

Target:

FGD5

Alternative Name: FGD5 (FGD5 Antibody Abstract)

Synonyms: ZFYVE23, C330025N11Rik, mFLJ00274, FYVE, RhoGEF and PH domain containing 5, Fgd5, FGD5

Background: FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation. It may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation and may play a role in regulating the actin cytoskeleton and cell shape.
Protein Interaction Partner: JMJD6, SUV39H1, Dlg4,
Protein Size: 540

Molecular Weight: 59 kDa

Gene ID: 152273