HENMT1 antibody (C-Term)

Catalog No. ABIN2791577

This Rabbit Polyclonal antibody specifically detects HENMT1 in WB. It exhibits reactivity toward Human.

Quick Overview for HENMT1 antibody (C-Term) (ABIN2791577)

Target: HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HENMT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HENMT1 Antibody

Binding Specificity: C-Term

Sequence: QVESLRVSHL PRRKEQAGER GDKPKDIGGS KAPVPCFGPV FTEVEKAKIE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against HENMT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HENMT1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HENMT1

Target: HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))

Alternative Name: HENMT1

Background: HENMT1 is a methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Alias Symbols: C1orf59, HEN1
Protein Interaction Partner: TRAF2, UBC,
Protein Size: 393

Molecular Weight: 44 kDa

Gene ID: 113802

NCBI Accession: NM_144584, NP_653185

UniProt: Q5T8I9