HIST1H2AE antibody (N-Term)

Catalog No. ABIN2791579

This Rabbit Polyclonal antibody specifically detects HIST1H2AE in WB. It exhibits reactivity toward Human, Cow, Rat, Mouse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Horse and Dog.

Quick Overview for HIST1H2AE antibody (N-Term) (ABIN2791579)

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Reactivity: Human, Cow, Rat, Mouse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2AE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIST1H2AE Antibody

Binding Specificity: N-Term

Sequence: GKQGGKARAK AKTRSSRAGL QFPVGRVHRL LRKGNYSERV GAGAPVYLAA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HIST1H2AE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H2AE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIST1H2AE

Target: HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))

Alternative Name: HIST1H2AE

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Alias Symbols: H2A.1, H2A.2, H2A/a, H2AFA
Protein Interaction Partner: UBC, HUWE1, SUZ12, EZH2, ITGA4, CAND1, COPS5, CUL1, CUL4A, CUL4B, CUL5, NFX1, NEDD8, TONSL, SUMO1, EID1, UHRF1, NAP1L4,
Protein Size: 130

Molecular Weight: 14 kDa

Gene ID: 3012

NCBI Accession: NM_021052, NP_066390

UniProt: P04908

Pathways: Telomere Maintenance