INTS2 antibody (N-Term)

Catalog No. ABIN2791590

The Rabbit Polyclonal anti-INTS2 antibody (ABIN2791590) specifically detects INTS2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio) samples.

Quick Overview for INTS2 antibody (N-Term) (ABIN2791590)

Target: INTS2 (Integrator Complex Subunit 2 (INTS2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-INTS2 Antibody

Binding Specificity: N-Term

Sequence: VCRGLIKNGE RQDEESLGGR RRTDALRFLC KMNPSQALKV RGMVVEECHL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against INTS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human INTS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTS2

Target: INTS2 (Integrator Complex Subunit 2 (INTS2))

Alternative Name: INTS2

Background: INTS2 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1.
Alias Symbols: INT2, KIAA1287
Protein Interaction Partner: KDM1A, SUV39H1, SOX2, UBC, INTS7, SNX4, ATP6V1B2, ATP6V1B1, INTS8, INTS10, CPSF3L, SHFM1, INTS5, INTS3, INTS6, INTS1,
Protein Size: 1204

Molecular Weight: 134 kDa

Gene ID: 57508

NCBI Accession: NM_020748, NP_065799

UniProt: Q9H0H0