Keratin 78 antibody (Middle Region)

Catalog No. ABIN2791630

This Rabbit Polyclonal antibody specifically detects Keratin 78 in WB. It exhibits reactivity toward Human, Cow, Dog, Guinea Pig, Mouse, Rabbit, Rat, Horse and Sheep.

Quick Overview for Keratin 78 antibody (Middle Region) (ABIN2791630)

Target: Keratin 78 (KRT78)

Reactivity: Human, Cow, Dog, Guinea Pig, Mouse, Rabbit, Rat, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 78 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Keratin 78 Antibody

Binding Specificity: Middle Region

Purpose: KRT78 Antibody - middle region

Sequence: TQASDTSVVL SMDNNRYLDF SSIITEVRAR YEEIARSSKA EAEALYQTK

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against KRT78. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human KRT78

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70732-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Keratin 78

Target: Keratin 78 (KRT78)

Alternative Name: KRT78

Background:

Background Information: This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.

Alternative Symbols: K5B, K78, Kb40, CK-78

Protein Name: Keratin, type II cytoskeletal 78

Molecular Weight: 45kDa

Gene ID: 196374

UniProt: Q8N1N4