Keratin 84 antibody (N-Term)

Catalog No. ABIN2791634

This Rabbit Polyclonal antibody specifically detects Keratin 84 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, Pig, Guinea Pig and Dog.

Quick Overview for Keratin 84 antibody (N-Term) (ABIN2791634)

Target: Keratin 84 (KRT84)

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, Pig, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 84 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Keratin 84 Antibody

Binding Specificity: N-Term

Purpose: KRT84 Antibody - N-terminal region

Sequence: VTINESLLVP LALEIDPTVQ RVKRDEKEQI KCLNNRFASF INKVRFLEQK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 83%

Characteristics: This is a rabbit polyclonal antibody against KRTHB2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human KRT84

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70739-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Keratin 84

Target: Keratin 84 (KRT84)

Alternative Name: KRT84

Background:

Background Information: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin is contained primarily in the filiform tongue papilla, among other hair keratins.

Gene Name: keratin 84, type II

Alternative Symbols: HB4, KRTHB4

Protein Name: keratin, type II cuticular Hb4

Molecular Weight: 56kDa

Gene ID: 3890

NCBI Accession: NP_149034

UniProt: Q9NSB2