MRPL2 antibody (N-Term)

Catalog No. ABIN2791668

The Rabbit Polyclonal anti-MRPL2 antibody (ABIN2791668) specifically detects MRPL2 in WB. The antibody is reactive with Human, Cow, Dog, Horse, Pig and Rabbit samples.

Quick Overview for MRPL2 antibody (N-Term) (ABIN2791668)

Target: MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL2 Antibody

Binding Specificity: N-Term

Purpose: MRPL2 Antibody - N-terminal region

Sequence: GGGHKQRYRM IDFLRFRPEE TKSGPFEEKV IQVRYDPCRS ADIALVAGGS

Predicted Reactivity: Cow: 80%, Dog: 87%, Horse: 93%, Human: 100%, Pig: 80%, Rabbit: 80%

Characteristics: This is a rabbit polyclonal antibody against MRPL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MRPL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70880-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL2

Target: MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))

Alternative Name: MRPL2

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q.

Alternative Symbols: CGI-22, RPML14, MRP-L14

Protein Name: 39S ribosomal protein L2, mitochondrial

Molecular Weight: 33kDa

Gene ID: 51069

NCBI Accession: NP_057034

UniProt: Q5T653