MRPL52 antibody (N-Term)

Catalog No. ABIN2791671

This Rabbit Polyclonal antibody specifically detects MRPL52 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for MRPL52 antibody (N-Term) (ABIN2791671)

Target: MRPL52 (Mitochondrial Ribosomal Protein L52 (MRPL52))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL52 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL52 Antibody

Binding Specificity: N-Term

Purpose: MRPL52 Antibody - N-terminal region

Sequence: MKGQLRRKAE RETFARRVVL LSQEMDAGLQ AWQLRQQKLQ EEQRKQENAL

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 91%, Pig: 86%, Rabbit: 86%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against MRPL52. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MRPL52

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70885-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL52

Target: MRPL52 (Mitochondrial Ribosomal Protein L52 (MRPL52))

Alternative Name: MRPL52

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which has no bacterial homolog. Multiple transcript variants encoding different protein isoforms were identified through sequence analysis.

Protein Name: 39S ribosomal protein L52, mitochondrial

Molecular Weight: 7kDa

Gene ID: 122704

UniProt: Q86TS9