UNC119B antibody (N-Term)

Catalog No. ABIN2791976

This Rabbit Polyclonal antibody specifically detects UNC119B in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Guinea Pig, Rabbit and Rat.

Quick Overview for UNC119B antibody (N-Term) (ABIN2791976)

Target: UNC119B (Unc-119 Homolog B (UNC119B))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC119B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UNC119B Antibody

Binding Specificity: N-Term

Purpose: UNC119B Antibody - N-terminal region

Sequence: AASAAGPGGL VAGKEEKKKA GGGVLNRLKA RRQAPHHAAD DGVGAAVTEQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against UNC119B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human UNC119B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP71940-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for UNC119B

Target: UNC119B (Unc-119 Homolog B (UNC119B))

Alternative Name: UNC119B

Background:

Background Information: UNC119B is a myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. It binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. UNC119B does not bind all myristoylated proteins and probably plays a role in trafficking proteins in photoreceptor cells.

Alternative Symbols: POC7B

Protein Name: Protein unc-119 homolog B

Molecular Weight: 28kDa

Gene ID: 84747

NCBI Accession: NP_001074002

UniProt: A6NIH7