DUX1 antibody (Middle Region)

Catalog No. ABIN2792016

The Rabbit Polyclonal anti-DUX1 antibody is suitable to detect DUX1 in samples from Human and Dog. It has been validated for WB.

Quick Overview for DUX1 antibody (Middle Region) (ABIN2792016)

Target: DUX1 (Double Homeobox 1 (DUX1))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DUX1 Antibody

Binding Specificity: Middle Region

Purpose: DUX1 Antibody - middle region

Sequence: ACFERNPYPG IATRERLAQA IGIPEPRVQI WFQNERSRQL RQHRRESRPW

Predicted Reactivity: Dog: 77%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against DUX4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DUX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72194-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DUX1

Target: DUX1 (Double Homeobox 1 (DUX1))

Alternative Name: DUX1

Background:

Background Information: The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX1, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]

Gene Name: double homeobox 1

Protein Name: double homeobox protein 1

Molecular Weight: 75kDa

Gene ID: 26584

NCBI Accession: NP_036278

UniProt: O43812