Transportin 3 antibody (C-Term)

Catalog No. ABIN2792069

The Rabbit Polyclonal anti-Transportin 3 antibody has been validated for WB. It is suitable to detect Transportin 3 in samples from Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Transportin 3 antibody (C-Term) (ABIN2792069)

Target: Transportin 3 (TNPO3)

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transportin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Transportin 3 Antibody

Binding Specificity: C-Term

Sequence: LCIPTFQLLE QQNGLQNHPD TVDDLFRLAT RFIQRSPVTL LRSQVVIPIL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against TNPO3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TNPO3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Transportin 3

Target: Transportin 3 (TNPO3)

Alternative Name: TNPO3

Background: The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.
Protein Interaction Partner: UBC, SUMO1, NEDD8, ELAC2, IPO9, TTLL12, PFDN6, ARPC2, ACTR3, PPP3CA, PPP2R1A, PPP2CA, HNRNPH1, FEN1, ALDOA, CLK3, CLK2, EGFR, SOX2, SMURF2, CFTR, VCP, CA9, UBE3A, TNPO1, CHMP3, ELAVL1, USP19, TRA2B, SRSF1, C20orf24, BRF2, PHLDA3,
Protein Size: 859

Molecular Weight: 94 kDa

Gene ID: 23534

Pathways: Protein targeting to Nucleus