Sorbs2 antibody (Middle Region)

Catalog No. ABIN2792074

This Rabbit Polyclonal antibody specifically detects Sorbs2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for Sorbs2 antibody (Middle Region) (ABIN2792074)

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorbs2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Sorbs2 Antibody

Binding Specificity: Middle Region

Sequence: LRPRDRSSTE KHDWDPPDRK VDTRKFRSEP RSIFEYEPGK SSILQHERPA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SORBS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SORBS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Alternative Name: SORBS2

Background: SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.
Alias Symbols: ARGBP2, PRO0618
Protein Interaction Partner: ATPAF2, SH2D4A, VPS37C, EFS, SORBS2, NCK2, YWHAE, WAS, SUZ12, YWHAB, BAG3, HCVgp1, YWHAZ, MDM2, AKT2, nef, WASF1, ADAM15, PTPN12, ABL1, ACTN1, PALLD, SEMA6A, NR1H2, EGFR, DLGAP4, DLGAP1, DLGAP2, SYNJ1, FLOT1, PAK2, RPL9, PAK1, TRAF4, PTK2B, VCL, PKM, CBL,
Protein Size: 644

Molecular Weight: 70 kDa

Gene ID: 8470

NCBI Accession: NM_001145670, NP_001139142