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Sorbs2 antibody (Middle Region)
Sorbs2
Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Sorbs2 Antibody
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Target
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Sorbs2
(Sorbin and SH3 Domain Containing 2 (Sorbs2))
Binding Specificity
All epitopes for Sorbs2 antibodies
Middle Region
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Host
All hosts for Sorbs2 antibodies
Rabbit
Clonality
All clonalities for Sorbs2 antibodies
Polyclonal
Conjugate
All conjugates for Sorbs2 antibodies
This Sorbs2 antibody is un-conjugated
Application
All applications for Sorbs2 antibodies
Western Blotting (WB)
Sequence
LRPRDRSSTE KHDWDPPDRK VDTRKFRSEP RSIFEYEPGK SSILQHERPA
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against SORBS2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human SORBS2
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for Sorbs2
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Target
Sorbs2
(Sorbin and SH3 Domain Containing 2 (Sorbs2))
Alternative Name
SORBS2 (Sorbs2 Products )
Synonyms
Argbp2 antibody, 2010203O03Rik antibody, 9430041O17Rik antibody, A530071H08 antibody, mKIAA0777 antibody, argbp2 antibody, pro0618 antibody, 9430041O17RIK antibody, DKFZp468F1119 antibody, ARGBP2 antibody, PRO0618 antibody, sorbin and SH3 domain containing 2 antibody, Sorbs2 antibody, SORBS2 antibody, sorbs2 antibody
Background
SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Alias Symbols: ARGBP2, PRO0618 Protein Interaction Partner: ATPAF2, SH2D4A, VPS37C, EFS, SORBS2, NCK2, YWHAE, WAS, SUZ12, YWHAB, BAG3, HCVgp1, YWHAZ, MDM2, AKT2, nef, WASF1, ADAM15, PTPN12, ABL1, ACTN1, PALLD, SEMA6A, NR1H2, EGFR, DLGAP4, DLGAP1, DLGAP2, SYNJ1, FLOT1, PAK2, RPL9, PAK1, TRAF4, PTK2B, VCL, PKM, CBL, Protein Size: 644
Molecular Weight
70 kDa
Gene ID
8470
NCBI Accession
NM_001145670 , NP_001139142
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