CDK3 antibody (C-Term)

Catalog No. ABIN2792151

This Rabbit Polyclonal antibody specifically detects CDK3 in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog and Rabbit.

Quick Overview for CDK3 antibody (C-Term) (ABIN2792151)

Target: CDK3 (Cyclin-Dependent Kinase 3 (CDK3))

Reactivity: Human, Mouse, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDK3 Antibody

Binding Specificity: C-Term

Sequence: NLEPEGRDLL MQLLQYDPSQ RITAKTALAH PYFSSPEPSP AARQYVLQRF

Predicted Reactivity: Cow: 81%, Dog: 86%, Human: 100%, Mouse: 93%, Rabbit: 87%

Characteristics: This is a rabbit polyclonal antibody against CDK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDK3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 305 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK3

Target: CDK3 (Cyclin-Dependent Kinase 3 (CDK3))

Alternative Name: CDK3

Background: CDK3 is a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0.This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: CDKN1A, STIP1, SKP2, SKP1, EEF1A2, CKS1B, CDKN1B, CDK3, CCNE1, CCNA2, STK4, STK3, CDK5, CDK2, RB1, CCNC, CCNE2, UBC, PPARA, HSP90AA1, APP, COPS5, COPS6, CUL1, ARRB2, CDK5R1, NEDD4L, EIF2AK2, CABLES1, CABLES2, KIR3DL1, CDC37, E2F3, E2F2, E2F1, CDKN3, TFDP1
Protein Size: 305

Molecular Weight: 35 kDa

Gene ID: 1018

NCBI Accession: NM_001258, NP_001249

UniProt: Q00526

Pathways: Cell Division Cycle