Cyclin G1 antibody (N-Term)

Catalog No. ABIN2792152

The Rabbit Polyclonal anti-Cyclin G1 antibody has been validated for WB and IHC. It is suitable to detect Cyclin G1 in samples from Human, Mouse, Rat, Cow, Pig and Dog.

Quick Overview for Cyclin G1 antibody (N-Term) (ABIN2792152)

Target: Cyclin G1 (CCNG1)

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin G1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cyclin G1 Antibody

Binding Specificity: N-Term

Sequence: IEVLTTTDSQ KLLHQLNALL EQESRCQPKV CGLRLIESAH DNGLRMTARL

Predicted Reactivity: Cow: 100%, Dog: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CCNG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCNG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 295 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin G1

Target: Cyclin G1 (CCNG1)

Alternative Name: CCNG1

Background: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. CCNG1 is a member of the cyclin family and contains the cyclin box. It lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: CCNG
Protein Interaction Partner: KRTAP10-7, SPERT, KRT40, LZTS2, HMBOX1, PAK7, TFIP11, RBPMS, TNIP1, PNMA1, SHKBP1, PLEKHA4, TFAP2C, NFATC4, LTBP3, GRN, APP, UBC, CDK2, TP73, TP53, PPP2CA, GAK, PPP2R4, CDKN2A, COX2, MDM2, CDK5,
Protein Size: 295

Molecular Weight: 34 kDa

Gene ID: 900

NCBI Accession: NM_004060, NP_004051

UniProt: P51959

Pathways: p53 Signaling