Cyclin G2 antibody (N-Term)

Catalog No. ABIN2792163

This Rabbit Polyclonal antibody specifically detects Cyclin G2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow and Dog.

Quick Overview for Cyclin G2 antibody (N-Term) (ABIN2792163)

Target: Cyclin G2 (CCNG2)

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin G2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin G2 Antibody

Binding Specificity: N-Term

Sequence: MKDLGAEHLA GHEGVQLLGL LNVYLEQEER FQPREKGLSL IEATPENDNT

Predicted Reactivity: Cow: 91%, Dog: 91%, Human: 100%, Mouse: 83%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against CCNG2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCNG2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 344 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin G2

Target: Cyclin G2 (CCNG2)

Alternative Name: CCNG2

Background: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53 % identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.
Protein Interaction Partner: EFHC2, FAM208B, NRIP2, UBC, SKP2, SKP1, PPP2CA, PPP2R4, PPP2R5C, PPP2R5B,
Protein Size: 344

Molecular Weight: 39 kDa

Gene ID: 901

NCBI Accession: NM_004354, NP_004345

UniProt: Q16589