Cyclin G2 antibody (AA 20-100)

Catalog No. ABIN7227658

The Rabbit Polyclonal anti-Cyclin G2 antibody is suitable to detect Cyclin G2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for Cyclin G2 antibody (AA 20-100) (ABIN7227658)

Target: Cyclin G2 (CCNG2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin G2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cyclin G2 Antibody

Binding Specificity: AA 20-100

Purpose: Rabbit Anti-CCNG2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CCNG2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCNG2 protein at AA range: 20-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cyclin G2

Target: Cyclin G2 (CCNG2)

Alternative Name: CCNG2

Background: Cyclin-G2CCNG2 (Cyclin G2) is a Protein Coding gene. Among its related pathways are FoxO signaling pathway and DNA Damage Response. The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53 % identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.

Molecular Weight: 37kD

Gene ID: 901

UniProt: Q16589