CCR4 antibody (Middle Region)

Catalog No. ABIN2792190

The Rabbit Polyclonal anti-CCR4 antibody (ABIN2792190) specifically detects CCR4 in WB. The antibody is reactive with Human, Mouse, Rat, Cow and Dog samples.

Quick Overview for CCR4 antibody (Middle Region) (ABIN2792190)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCR4 Antibody

Binding Specificity: Middle Region

Purpose: CCR4 Antibody - middle region

Sequence: TERNHTYCKT KYSLNSTTWK VLSSLEINIL GLVIPLGIML FCYSMIIRTL

Predicted Reactivity: Cow: 87%, Dog: 87%, Human: 100%, Mouse: 87%, Rat: 87%

Characteristics: This is a rabbit polyclonal antibody against CCR4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCR4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CCR4

Background:

Background Information: CCR4 belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1657 BC071751.1 1-1657

Gene Name: Chemokine (C-C motif) receptor 4

Alternative Symbols: CKR4, K5-5, CD194, CMKBR4, ChemR13, CC-CKR-4, HGCN:14099

Protein Name: C-C chemokine receptor type 4

Molecular Weight: 41kDa

Gene ID: 1233

NCBI Accession: NP_005499

UniProt: P51679