RGS3 antibody (C-Term)

Catalog No. ABIN2792209

This anti-RGS3 antibody is a Rabbit Polyclonal antibody detecting RGS3 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Pig, Guinea Pig and Rabbit.

Quick Overview for RGS3 antibody (C-Term) (ABIN2792209)

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS3 Antibody

Binding Specificity: C-Term

Sequence: KDNLQSVTRG CFDLAQKRIF GLMEKDSYPR FLRSDLYLDL INQKKMSPPL

Specificity: Isoforms 1-4 & 6 of P49796

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RGS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RGS3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 519 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS3

Target: RGS3 (Regulator of G-Protein Signaling 3 (RGS3))

Alternative Name: RGS3

Background: RGS3 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
Alias Symbols: C2PA, FLJ20370, FLJ31516, FLJ90496, PDZ-RGS3, RGP3
Protein Interaction Partner: GORASP2, UBC, PLSCR1, SUMO2, HES4, GNAI2, GNA11, APP, ACD, ARRB1, Nedd4, IRF5, ISG15, CNKSR2, PAX6, GLS2, YWHAE, HIPK3, PARK2, MAPK12, RGS3, YWHAB, YWHAZ, EFNB2, SCN5A, EFNB1, YWHAQ, GNAI3, GRIN2A, ESR1,
Protein Size: 519

Molecular Weight: 57 kDa

Gene ID: 5998

NCBI Accession: NM_021106, NP_066929

UniProt: P49796

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling