MMP10 antibody (N-Term)

Catalog No. ABIN2792218

The Rabbit Polyclonal anti-MMP10 antibody is suitable to detect MMP10 in samples from Human. It has been validated for WB.

Quick Overview for MMP10 antibody (N-Term) (ABIN2792218)

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP10 Antibody

Binding Specificity: N-Term

Purpose: MMP10 Antibody - N-terminal region

Sequence: MMHLAFLVLL CLPVCSAYPL SGAAKEEDSN KDLAQQYLEK YYNLEKDVKQ

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MMP10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MMP10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMP10

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Alternative Name: MMP10

Background:

Background Information: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene Name: Matrix metallopeptidase 10 (stromelysin 2)

Alternative Symbols: SL-2, STMY2

Protein Name: Stromelysin-2

Molecular Weight: 54kDa

Gene ID: 4319

NCBI Accession: NP_002416

UniProt: P09238