PDE1B antibody (Middle Region)
Quick Overview for PDE1B antibody (Middle Region) (ABIN2792238)
Target
See all PDE1B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- VKRIQENKQK WKERAASGIT NQMSIDELSP CEEEAPPSPA EDEHNQNGNL
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Predicted Reactivity
- Cow: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 100%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against PDE1B. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PDE1B
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 536 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
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Alternative Name
- PDE1B
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Background
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PDE1B has a preference for cGMP as a substrate.
Alias Symbols: PDE1B1, PDES1B
Protein Interaction Partner: POT1, UBE3A,
Protein Size: 536 -
Molecular Weight
- 61 kDa
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Gene ID
- 5153
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NCBI Accession
- NM_000924, NP_000915
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UniProt
- Q01064
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Pathways
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Target
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