CHML antibody (N-Term)

Catalog No. ABIN2792246

This Rabbit Polyclonal antibody specifically detects CHML in WB. It exhibits reactivity toward Human.

Quick Overview for CHML antibody (N-Term) (ABIN2792246)

Target: CHML (Choroideremia-Like (Rab Escort Protein 2) (CHML))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHML antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHML Antibody

Binding Specificity: N-Term

Purpose: CHML Antibody - N-terminal region

Sequence: NPSLGVSNTF TEVLDSALPE ESQLSYFNSD EMPAKHTQKS DTEISLEVTD

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CHML. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHML

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHML

Target: CHML (Choroideremia-Like (Rab Escort Protein 2) (CHML))

Alternative Name: CHML

Background:

Background Information: The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II.

Gene Name: Choroideremia-like (Rab escort protein 2)

Alternative Symbols: REP2

Protein Name: Rab proteins geranylgeranyltransferase component A 2

Molecular Weight: 74kDa

Gene ID: 1122

NCBI Accession: NP_001812

UniProt: P26374