CHRND antibody (N-Term)

Catalog No. ABIN2792255

The Rabbit Polyclonal anti-CHRND antibody is suitable to detect CHRND in samples from Human, Rat, Dog, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig and Pig. It has been validated for WB and IHC.

Quick Overview for CHRND antibody (N-Term) (ABIN2792255)

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Reactivity: Human, Rat, Dog, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRND antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CHRND Antibody

Binding Specificity: N-Term

Purpose: CHRND Antibody - N-terminal region

Sequence: LTLGLLAALA VCGSWGLNEE ERLIRHLFQE KGYNKELRPV AHKEESVDVA

Predicted Reactivity: Cow: 91%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Pig: 100%, Rabbit: 86%, Rat: 85%, Zebrafish: 78%

Characteristics: This is a rabbit polyclonal antibody against CHRND. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRND

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRND

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Alternative Name: CHRND

Background:

Targeted Subunit: delta

Background Information: The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Gene Name: Cholinergic receptor, nicotinic, delta (muscle)

Alternative Symbols: ACHRD, CMS2A, CMS3A, CMS3B, CMS3C, FCCMS, SCCMS

Protein Name: Acetylcholine receptor subunit delta

Molecular Weight: 59kDa

Gene ID: 1144

NCBI Accession: NP_000742

UniProt: Q07001