OPRK1 antibody (N-Term)

Catalog No. ABIN2792280

The Rabbit Polyclonal anti-OPRK1 antibody has been validated for WB. It is suitable to detect OPRK1 in samples from Human, Mouse, Pig and Guinea Pig.

Quick Overview for OPRK1 antibody (N-Term) (ABIN2792280)

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reactivity: Human, Mouse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OPRK1 Antibody

Binding Specificity: N-Term

Sequence: DSPIQIFRGE PGPTCAPSAC LPPNSSAWFP GWAEPDSNGS AGSEDAQLEP

Predicted Reactivity: Guinea Pig: 91%, Human: 100%, Mouse: 84%, Pig: 85%

Characteristics: This is a rabbit polyclonal antibody against OPRK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OPRK1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 380 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Alternative Name: OPRK1

Background: OPRK1 is a multi-pass membrane protein. It belongs to the G-protein coupled receptor 1 family. OPRK1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for dynorphins. OPRK1 may play a role in arousal and regulation of autonomic and neuroendocrine functions.
Alias Symbols: KOR, OPRK
Protein Interaction Partner: GPRASP1, GABARAPL1, SLC9A3R1, OPRD1, GNA15, UBC,
Protein Size: 380

Molecular Weight: 43 kDa

Gene ID: 4986

NCBI Accession: NM_000912, NP_000903

UniProt: P41145