SNAP25 antibody (C-Term)

Catalog No. ABIN2792294

This Rabbit Polyclonal antibody specifically detects SNAP25 in WB. It exhibits reactivity toward Rat, Dog and Guinea Pig.

Quick Overview for SNAP25 antibody (C-Term) (ABIN2792294)

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Reactivity: Rat, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAP25 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNAP25 Antibody

Binding Specificity: C-Term

Sequence: IGNLRHMALD MGNEIDTQNR QIDRIMEKAD SNKTRIDEAN QRATKMLGSG

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SNAP25. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse SNAP25

Application Details

Application Notes: WB Suggested Anti-SNAP25 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human Frontal cortex.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 206 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNAP25

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Alternative Name: SNAP25

Background: Snap25 contains 2 t-SNARE coiled-coil homology domains and belongs to the SNAP-25 family. t-SNARE involved in the molecular regulation of neurotransmitter release. Snap25 may play an important role in the synaptic function of specific neuronal systems. Snap25 associates with proteins involved in vesicle docking and membrane fusion.
Alias Symbols: sp, Bdr, SNAP-25
Protein Interaction Partner: Vamp2, Hrs2, Hgs, Stx1a, Htt, Snca, Dnajc5, Stx4, Stx3, Stx2, Sgta, Ubc, Hspa8, Zdhhc17, Zdhhc7, Zdhhc3, Snap25,
Protein Size: 206

Molecular Weight: 23 kDa

Gene ID: 20614

NCBI Accession: NM_011428, NP_035558

UniProt: P60879

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport